While both of these are moderate in terms of interactions, combining this can make you feel a little bit dizzy, drowsy, and also you may struggle with thinking, concentration, and also help with the motor coordination. Both of these can help with insomnia and are both considered sedative. 

What Melatonin Is 

Melatonin is basically a hormone that’s already present in your body, and secreting it actually helps with controlling the biological clock. It’s available as an over-the-counter medicine and used as a type of sleep aid that can help you. 

Melatonin is one that’s naturally produced by your pineal gland, and it can help with the circadian rhythms, your sleep and wake cycle, and also regulates the blood pressure, protects your body from oxidative stress, and also can help with inflammation, cancer, and also is considered a neuroprotective. this does naturally decrease as you get older, and blue light is also a big part of this. 

It can be used for a lot of different issues with sleep, including the following: 

• Jet lag
• Insomnia 
• Sleeping shifts that are making it harder to sleep, such as different work schedules. 
• The non-24 hour sleep disorder, where you can’t have a properly synchronized biological clock. 

This is used mostly as a supplement to help with sleep. There are also extended release versions too where it takes longer to get the full dosage. 

Melatonin does bind to various receptors in the body, and the promotion of sleep is actually tied to the activation of your M1 receptors. There is also the M2 receptors, which are responsible for phasing your clock into different cycles, and you usually also use this to regulate it. 

The MT3 hormone I sone that’s a detox one and is responsible for helping to make sure that you reduce the result of the fight or flight response. 

Benefits and Drawbacks Of Mixing 

While this can cause some drug interactions, it’s not totally uncommon to use CBD products with the melatonin of the body, in order to help with the promotion of rest. 

This of course can help as well and may be enhanced as well if you take THC and CBN too. 

The benefits of usually involve the following: 

• Gets you asleep and lets you stay asleep in most cases 
• Can help with the melatonin production, so that the melatonin dosages are done to a level that you desire 
• There isn’t much harm 

There are a few risks that can happen if you do mix them, albeit they’re mild as well: 

• They’re not good for long-term problems with insomnia. 
• It can make you feel a little bit more groggy.  You also may deal with melatonin overdose, and it can also create nausea in the body that’s there 
• It can increase the REM sleep time, but cannabis decreases this however there is no found effect that this has on someone 

It can actually help you with this tough, since mixing this actually can reduce the amount of time that you need to use the melatonin that’s there improving the efficiency of this. It also can reduce the need for more melatonin, reducing the chance for overdose too. 

It can, however, also help with rem sleep too, as this is used in a lot of cases to help with improving your ability o metabolize things. Right now though, ther isn’t much known that’s totally sure, and there are some both negative and positive effects that come with this, so use your own discretion when trying to consume this type of supplements.